Structure and Reactivity Group

From structure to properties...

New methodologies based on quantitative structure-property/activity relationships (QSP/AR) are being increasingly used for interpretation and prediction of all sorts of biological and physicochemical processes. However, the analysis and prediction of properties or behaviors relies upon accurate and reproducible experimental data, as well as on rigorous and well-validated physicochemical models. A significant part of SRG research activities explore this type of methodologies. More...

In the quest of new drugs...

The rational design, synthesis and evaluation of new molecules with relevant public health impact, e.g., new antitubercular compounds, as well as the identification of new leads to treat age-related diseases such as cancer and CNS disorders, from marine natural sources collected in Portuguese waters, constitute two important lines of investigation of SRG. More...

Towards a cleaner environment

The progressive elimination of VOCs in industrial settings keeps stimulating researchers to develop new, clean, secure and energetically efficient solvent systems. Furthermore, the unremitting emission of CO₂ to the atmosphere, widely recognized as one of the major sources of the greenhouse effect, renders any (new) solvent-oriented strategy to capture this gas an interesting challenge. SRG extensive know-how on thermodynamic and physicochemical characterization of solvents is a major asset to actively help finding “greener” and more efficient solvent media. More...